Prostate Cancer Detected by Choroidal Tumor and Complete Response to Hormonal Therapy: Case Report and Literature Review of 24 Patients With Choroidal Metastasis From Prostate Cancer

Metastatic choroidal tumors derived from prostate cancer are rare. In this study, we report a patient who manifested tumor as the initial presenting sign of and review 23 patients with metastasis in literature to answer clinical question how metastases would respond hormonal therapy. A 73-year-old man presented right eye. He was good health had no previous history except for current hemodialysis 3 years due chronic renal failure sequel glomerulonephritis. With diagnosis probable metastatic tumor, positron emission tomography performed disclose high-uptake sites multiple bones, lymph nodes, prostate, together nodular lesions bilateral lungs on computed (CT) scan. Serum prostate-specific antigen (PSA) elevated 541 ng/mL, which supported primary site. degarelix injection, resolved rapidly became flat degeneration month. Prostate biopsy showed poorly differentiated adenocarcinoma, he underwent surgical castration. medication until later when gradual increase serum PSA up 6.05 ng/mL bony CT Bicalutamide, switched enzalutamide then abiraterone, led undetectable level last visit relapse metastasis, 6.8 after visit. 24 cancer, including patient, 8 mostly complete response Among 13 were frequently course therapy, or partial external beam radiation eye 11 episcleral plaque radiotherapy 2 patients. conclusion, show therapy has not been initiated. Hormone-resistant therapeutic could be managed successfully by